Information system of any organization, associated with its structure that is based on technology, to collect information and manage tasks and people. For introducing and executing new information systems, a company applies changes to its hardware as well software system, management, skills, and structure of the organization. In the following study, three topics related to the new Information system and business organization have been selected to explain. These topics are the effect of new information systems on organizations, the development process of new information systems, and risks associated with the project of information systems.